How to deal with non-detectable and outlying values in biomarker research: Best practices and recommendations for univariate imputation approaches

Non-detectable (ND) and outlying concentration values (OV) are a common challenge of biomarker investigations. However, best practices on how to aptly deal with the affected cases are still missing. The high methodological heterogeneity in biomarker-oriented research, as for example, in the field of...

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Detalles Bibliográficos
Autores principales: Herbers, Judith, Miller, Robert, Walther, Andreas, Schindler, Lena, Schmidt, Kornelius, Gao, Wei, Rupprecht, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9216349/
https://www.ncbi.nlm.nih.gov/pubmed/35757062
http://dx.doi.org/10.1016/j.cpnec.2021.100052

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9216349/
https://www.ncbi.nlm.nih.gov/pubmed/35757062
http://dx.doi.org/10.1016/j.cpnec.2021.100052

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