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How to deal with non-detectable and outlying values in biomarker research: Best practices and recommendations for univariate imputation approaches
Non-detectable (ND) and outlying concentration values (OV) are a common challenge of biomarker investigations. However, best practices on how to aptly deal with the affected cases are still missing. The high methodological heterogeneity in biomarker-oriented research, as for example, in the field of...
Autores principales: | Herbers, Judith, Miller, Robert, Walther, Andreas, Schindler, Lena, Schmidt, Kornelius, Gao, Wei, Rupprecht, Florian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9216349/ https://www.ncbi.nlm.nih.gov/pubmed/35757062 http://dx.doi.org/10.1016/j.cpnec.2021.100052 |
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