Maturation Delay of Human GABAergic Neurogenesis in Fragile X Syndrome Pluripotent Stem Cells

Fragile X Syndrome (FXS), the leading monogenic cause of intellectual disability and autism spectrum disorder, is caused by expansion of a CGG trinucleotide repeat in the 5ʹ-UTR of the Fragile X Mental Retardation-1 (FMR1) gene. Epigenetic silencing of FMR1 results in loss of the Fragile X Mental Re...

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Detalles Bibliográficos
Autores principales: Zhang, Ai, Sokolova, Irina, Domissy, Alain, Davis, Joshua, Rao, Lee, Hana Utami, Kagistia, Wang, Yanling, Hagerman, Randi J, Pouladi, Mahmoud A, Sanna, Pietro, Boland, Michael J, Loring, Jeanne F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Pluripotent Stem Cells
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9216490/
https://www.ncbi.nlm.nih.gov/pubmed/35556144
http://dx.doi.org/10.1093/stcltm/szac022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9216490/
https://www.ncbi.nlm.nih.gov/pubmed/35556144
http://dx.doi.org/10.1093/stcltm/szac022

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