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Transient Inhibition of the JNK Pathway Promotes Human Hematopoietic Stem Cell Quiescence and Engraftment

The widespread clinical application of cord blood (CB) for hematopoietic stem cell (HSC) transplantation is limited mainly by the inadequate number of hematopoietic stem and progenitor cells (HSPCs) in single CB units, which results in unsuccessful or delayed engraftment in recipients. The identific...

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Detalles Bibliográficos
Autores principales: Xie, Huangfan, Sun, Zhongjie, Xiao, Xiong, Liu, Defang, Qi, Hailong, Tian, Guoxiong, Chen, Miao, Chen, Ligong, Su, XunCheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9216500/
https://www.ncbi.nlm.nih.gov/pubmed/35427423
http://dx.doi.org/10.1093/stcltm/szac019