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Quantifying biochemical reaction rates from static population variability within incompletely observed complex networks

Quantifying biochemical reaction rates within complex cellular processes remains a key challenge of systems biology even as high-throughput single-cell data have become available to characterize snapshots of population variability. That is because complex systems with stochastic and non-linear inter...

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Detalles Bibliográficos
Autores principales: Wittenstein, Timon, Leibovich, Nava, Hilfinger, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9216546/
https://www.ncbi.nlm.nih.gov/pubmed/35731728
http://dx.doi.org/10.1371/journal.pcbi.1010183