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Evaluating the predictive accuracy of curated biological pathways in a public knowledgebase

ABSTRACT: Reactome is a database of human biological pathways manually curated from the primary literature and peer-reviewed by experts. To evaluate the utility of Reactome pathways for predicting functional consequences of genetic perturbations, we compared predictions of perturbation effects based...

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Detalles Bibliográficos
Autores principales: Wright, Adam J, Orlic-Milacic, Marija, Rothfels, Karen, Weiser, Joel, Trinh, Quang M, Jassal, Bijay, Haw, Robin A, Stein, Lincoln D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9216552/
https://www.ncbi.nlm.nih.gov/pubmed/35348650
http://dx.doi.org/10.1093/database/baac009