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Evaluating the predictive accuracy of curated biological pathways in a public knowledgebase
ABSTRACT: Reactome is a database of human biological pathways manually curated from the primary literature and peer-reviewed by experts. To evaluate the utility of Reactome pathways for predicting functional consequences of genetic perturbations, we compared predictions of perturbation effects based...
Autores principales: | Wright, Adam J, Orlic-Milacic, Marija, Rothfels, Karen, Weiser, Joel, Trinh, Quang M, Jassal, Bijay, Haw, Robin A, Stein, Lincoln D |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9216552/ https://www.ncbi.nlm.nih.gov/pubmed/35348650 http://dx.doi.org/10.1093/database/baac009 |
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