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Intramammary rapamycin administration to calves induces epithelial stem cell self-renewal and latent cell proliferation and milk protein expression

Mammary epithelial stem cells differentiate to create the basal and luminal layers of the gland. Inducing the number of differentiating bovine mammary stem cells may provide compensating populations for the milk-producing cells that die during lactation. Inhibition of mTOR activity by rapamycin sign...

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Detalles Bibliográficos
Autores principales: Kosenko, Anna, Jacoby, Shamay, Salame, Tomer-Meir, Ross, Maya, Barash, Itamar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9216576/
https://www.ncbi.nlm.nih.gov/pubmed/35731738
http://dx.doi.org/10.1371/journal.pone.0269505