SynLethDB 2.0: a web-based knowledge graph database on synthetic lethality for novel anticancer drug discovery

Two genes are synthetic lethal if mutations in both genes result in impaired cell viability, while mutation of either gene does not affect the cell survival. The potential usage of synthetic lethality (SL) in anticancer therapeutics has attracted many researchers to identify synthetic lethal gene pa...

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Detalles Bibliográficos
Autores principales: Wang, Jie, Wu, Min, Huang, Xuhui, Wang, Li, Zhang, Sophia, Liu, Hui, Zheng, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Database Update
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9216587/
https://www.ncbi.nlm.nih.gov/pubmed/35562840
http://dx.doi.org/10.1093/database/baac030

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9216587/
https://www.ncbi.nlm.nih.gov/pubmed/35562840
http://dx.doi.org/10.1093/database/baac030

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