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SynLethDB 2.0: a web-based knowledge graph database on synthetic lethality for novel anticancer drug discovery
Two genes are synthetic lethal if mutations in both genes result in impaired cell viability, while mutation of either gene does not affect the cell survival. The potential usage of synthetic lethality (SL) in anticancer therapeutics has attracted many researchers to identify synthetic lethal gene pa...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9216587/ https://www.ncbi.nlm.nih.gov/pubmed/35562840 http://dx.doi.org/10.1093/database/baac030 |