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Chemiluminescent immunoassay overestimates hormone concentrations and obscures testosterone sex differences relative to LC-MS/MS in a field study of diverse adolescents

BACKGROUND: Methodological comparisons of hormone quantification techniques have repeatedly demonstrated that, in adults, enzyme immunoassay (EIA) inflates steroid hormone concentrations relative to mass spectrometry. However, methodological comparisons in adolescent samples remain rare, and few stu...

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Detalles Bibliográficos
Autores principales: Chafkin, Julia E., O'Brien, Joseph M., Medrano, Fortunato N., Lee, Hae Yeon, Yeager, David S., Josephs, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9216594/
https://www.ncbi.nlm.nih.gov/pubmed/35755201
http://dx.doi.org/10.1016/j.cpnec.2022.100132