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COVID-19, vaccines and deficiency of ACE(2) and other angiotensinases. Closing the loop on the "Spike effect"

The role of a dysregulated renin-angiotensin system (RAS) in the pathogenesis of COVID-19 is well recognized. The imbalance between angiotensin II (Ang II) and Angiotensin(1-7) (Ang(1,7)) caused by the interaction between SARS-CoV-2 and the angiotensin converting enzyme 2 (ACE(2)) receptors exerts a...

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Detalles Bibliográficos
Autores principales: Angeli, Fabio, Reboldi, Gianpaolo, Trapasso, Monica, Zappa, Martina, Spanevello, Antonio, Verdecchia, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Federation of Internal Medicine. Published by Elsevier B.V. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9217159/
https://www.ncbi.nlm.nih.gov/pubmed/35753869
http://dx.doi.org/10.1016/j.ejim.2022.06.015