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Effective natural inhibitors targeting IGF-1R by computational study

IGF-1R belongs to a tyrosine kinase family and is currently a newly discovered drug target. IGF-1R inhibitors can bind directly to IGF-1R to achieve the effect of inhibiting the function of IGF-1R. At present, IGF-1R inhibitors have good clinical effects on Ewing sarcoma in the clinic. In this artic...

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Detalles Bibliográficos
Autores principales: Wang, Xinyu, Zhou, Pengcheng, Lin, Liangxin, Wu, Bo, Fu, Zhaoyu, Huang, Xing, Zhu, Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9217697/
https://www.ncbi.nlm.nih.gov/pubmed/35680570
http://dx.doi.org/10.18632/aging.204117