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FMNL2 regulates gliovascular interactions and is associated with vascular risk factors and cerebrovascular pathology in Alzheimer’s disease

Alzheimer’s disease (AD) has been associated with cardiovascular and cerebrovascular risk factors (CVRFs) during middle age and later and is frequently accompanied by cerebrovascular pathology at death. An interaction between CVRFs and genetic variants might explain the pathogenesis. Genome-wide, ge...

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Detalles Bibliográficos
Autores principales: Lee, Annie J., Raghavan, Neha S., Bhattarai, Prabesh, Siddiqui, Tohid, Sariya, Sanjeev, Reyes-Dumeyer, Dolly, Flowers, Xena E., Cardoso, Sarah A. L., De Jager, Philip L., Bennett, David A., Schneider, Julie A., Menon, Vilas, Wang, Yanling, Lantigua, Rafael A., Medrano, Martin, Rivera, Diones, Jiménez-Velázquez, Ivonne Z., Kukull, Walter A., Brickman, Adam M., Manly, Jennifer J., Tosto, Giuseppe, Kizil, Caghan, Vardarajan, Badri N., Mayeux, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9217776/
https://www.ncbi.nlm.nih.gov/pubmed/35608697
http://dx.doi.org/10.1007/s00401-022-02431-6