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Serum anti-malondialdehyde-acetaldehyde IgA antibody concentration improves prediction of coronary atherosclerosis beyond traditional risk factors in patients with rheumatoid arthritis

Patients with rheumatoid arthritis (RA) have increased atherosclerosis; oxidative stress may be a contributor. Oxidative stress produces immunogenic malondialdehyde-acetaldehyde (MAA) protein adducts and anti-MAA antibodies are detectable in human serum. We hypothesized that anti-MAA antibody concen...

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Detalles Bibliográficos
Autores principales: Lomzenski, Hannah E., Thiele, Geoffrey M., Duryee, Michael J., Chen, Sheau-Chiann, Ye, Fei, Anderson, Daniel R., Mikuls, Ted R., Ormseth, Michelle J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9217813/
https://www.ncbi.nlm.nih.gov/pubmed/35732827
http://dx.doi.org/10.1038/s41598-022-14954-9