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Molecular Pathogenesis of Sporadic Desmoid Tumours and Its Implications for Novel Therapies: A Systematised Narrative Review

Sporadic desmoid-type fibromatosis is a rare, fibroblastic soft-tissue neoplasm with local aggressiveness but no metastatic potential. Aberrant Wnt/β-catenin signalling has been extensively linked to desmoid pathogenesis, although little is known about other molecular drivers and no established trea...

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Detalles Bibliográficos
Autores principales: McLean, Thomas D., Duchi, Serena, Di Bella, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9217905/
https://www.ncbi.nlm.nih.gov/pubmed/35446005
http://dx.doi.org/10.1007/s11523-022-00876-z