Chronic inhibition of the mitochondrial ATP synthase in skeletal muscle triggers sarcoplasmic reticulum distress and tubular aggregates

Tubular aggregates (TA) are honeycomb-like arrays of sarcoplasmic-reticulum (SR) tubules affecting aged glycolytic fibers of male individuals and inducing severe sarcomere disorganization and muscular pain. TA develop in skeletal muscle from Tubular Aggregate Myopathy (TAM) patients as well as in ot...

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Detalles Bibliográficos
Autores principales: Sánchez-González, Cristina, Herrero Martín, Juan Cruz, Salegi Ansa, Beñat, Núñez de Arenas, Cristina, Stančič, Brina, Pereira, Marta P., Contreras, Laura, Cuezva, José M., Formentini, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9217934/
https://www.ncbi.nlm.nih.gov/pubmed/35732639
http://dx.doi.org/10.1038/s41419-022-05016-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9217934/
https://www.ncbi.nlm.nih.gov/pubmed/35732639
http://dx.doi.org/10.1038/s41419-022-05016-z

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