Efficacy and safety of ketone ester infusion to prevent muscle weakness in a mouse model of sepsis-induced critical illness

In septic mice, 3-hydroxybutyrate-sodium-salt has shown to partially prevent sepsis-induced muscle weakness. Although effective, the excessive sodium load was toxic. We here investigated whether ketone ester 3-hydroxybutyl-3-hydroxybutanoate (3HHB) was a safer alternative. In a mouse model of abdomi...

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Detalles Bibliográficos
Autores principales: Weckx, Ruben, Goossens, Chloë, Derde, Sarah, Pauwels, Lies, Vander Perre, Sarah, Van den Berghe, Greet, Langouche, Lies
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9217969/
https://www.ncbi.nlm.nih.gov/pubmed/35732826
http://dx.doi.org/10.1038/s41598-022-14961-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9217969/
https://www.ncbi.nlm.nih.gov/pubmed/35732826
http://dx.doi.org/10.1038/s41598-022-14961-w

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