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Modeling synergistic effects by using general Hill-type response surfaces describing drug interactions
The classification of effects caused by mixtures of agents as synergistic, antagonistic or additive depends critically on the reference model of ’null interaction’. Two main approaches to describe co-operative effects are currently in use, the Additive Dose (ADM) or concentration addition (CA) and t...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9217971/ https://www.ncbi.nlm.nih.gov/pubmed/35732854 http://dx.doi.org/10.1038/s41598-022-13469-7 |