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A phylogenetic approach to study the evolution of somatic mutational processes in cancer
Cancer cell genomes change continuously due to mutations, and mutational processes change over time in patients, leaving dynamic signatures in the accumulated genomic variation in tumors. Many computational methods detect the relative activities of known mutation signatures. However, these methods m...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9217972/ https://www.ncbi.nlm.nih.gov/pubmed/35732905 http://dx.doi.org/10.1038/s42003-022-03560-0 |