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Structural variants and modifications of hammerhead ribozymes targeting influenza A virus conserved structural motifs
The naturally occurring structure and biological functions of RNA are correlated, which includes hammerhead ribozymes. We proposed new variants of hammerhead ribozymes targeting conserved structural motifs of segment 5 of influenza A virus (IAV) (+)RNA. The variants carry structural and chemical mod...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9217987/ https://www.ncbi.nlm.nih.gov/pubmed/35784013 http://dx.doi.org/10.1016/j.omtn.2022.05.035 |