Cargando…

Structural variants and modifications of hammerhead ribozymes targeting influenza A virus conserved structural motifs

The naturally occurring structure and biological functions of RNA are correlated, which includes hammerhead ribozymes. We proposed new variants of hammerhead ribozymes targeting conserved structural motifs of segment 5 of influenza A virus (IAV) (+)RNA. The variants carry structural and chemical mod...

Descripción completa

Detalles Bibliográficos
Autores principales: Czapik, Tomasz, Piasecka, Julita, Kierzek, Ryszard, Kierzek, Elzbieta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9217987/
https://www.ncbi.nlm.nih.gov/pubmed/35784013
http://dx.doi.org/10.1016/j.omtn.2022.05.035