Pharmacokinetic Parameters of Oral Pegylated IFN-λ1

We studied the pharmacokinetics of a pegylated IFN-λ1 (PEG IFN-λ1) after its oral administration to rats in different therapeutic doses. The hypothesis on linear pharmacokinetics of PEG IFN-λ1 within the dose range of 2.6-7.8 μg/kg was confirmed, high for protein molecules bioavailability from 17.5...

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Detalles Bibliográficos
Autores principales: Sherstoboev, E. Yu., Oleinik, L. A., Zhdanov, V. V., Kikhtenko, N. A., Madonov, P. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9218048/
https://www.ncbi.nlm.nih.gov/pubmed/35737159
http://dx.doi.org/10.1007/s10517-022-05521-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9218048/
https://www.ncbi.nlm.nih.gov/pubmed/35737159
http://dx.doi.org/10.1007/s10517-022-05521-3

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