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Neutrophil extracellular traps (NETs) reduce the diffusion of doxorubicin which may attenuate its ability to induce apoptosis of ovarian cancer cells

PURPOSE: Although neutrophil extracellular traps (NETs) are present in various tumors, their roles in tumor biology have not been clarified yet. In this study, we examined how NETs affect the pharmacokinetics and effects of doxorubicin (DOX). METHODS: NETs were generated by neutrophils stimulated wi...

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Detalles Bibliográficos
Autores principales: Tamura, Kohei, Miyato, Hideyo, Kanamaru, Rihito, Sadatomo, Ai, Takahashi, Kazuya, Ohzawa, Hideyuki, Koyanagi, Takahiro, Saga, Yasushi, Takei, Yuji, Fujiwara, Hiroyuki, Lefor, Alan Kawarai, Sata, Naohiro, Kitayama, Joji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9218137/
https://www.ncbi.nlm.nih.gov/pubmed/35756123
http://dx.doi.org/10.1016/j.heliyon.2022.e09730