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Neutrophil extracellular traps (NETs) reduce the diffusion of doxorubicin which may attenuate its ability to induce apoptosis of ovarian cancer cells
PURPOSE: Although neutrophil extracellular traps (NETs) are present in various tumors, their roles in tumor biology have not been clarified yet. In this study, we examined how NETs affect the pharmacokinetics and effects of doxorubicin (DOX). METHODS: NETs were generated by neutrophils stimulated wi...
Autores principales: | Tamura, Kohei, Miyato, Hideyo, Kanamaru, Rihito, Sadatomo, Ai, Takahashi, Kazuya, Ohzawa, Hideyuki, Koyanagi, Takahiro, Saga, Yasushi, Takei, Yuji, Fujiwara, Hiroyuki, Lefor, Alan Kawarai, Sata, Naohiro, Kitayama, Joji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9218137/ https://www.ncbi.nlm.nih.gov/pubmed/35756123 http://dx.doi.org/10.1016/j.heliyon.2022.e09730 |
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