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Redox regulation by TXNRD3 during epididymal maturation underlies capacitation-associated mitochondrial activity and sperm motility in mice

During epididymal transit, redox remodeling protects mammalian spermatozoa, preparing them for survival in the subsequent journey to fertilization. However, molecular mechanisms of redox regulation in sperm development and maturation remain largely elusive. In this study, we report that thioredoxin-...

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Detalles Bibliográficos
Autores principales: Wang, Huafeng, Dou, Qianhui, Jeong, Kyung Jo, Choi, Jungmin, Gladyshev, Vadim N., Chung, Jean-Ju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9218152/
https://www.ncbi.nlm.nih.gov/pubmed/35643315
http://dx.doi.org/10.1016/j.jbc.2022.102077