Identification of G-quadruplex anti-Interleukin-2 aptamer with high specificity through SELEX stringency

Aptamers are short single-stranded oligonucleotides capable of binding to various targets with high specificity and affinity. This study aimed to identify an aptamer against mouse interleukin-2 (mIL-2) as one of the most important cytokines in autoimmune diseases for diagnostic and therapeutic purpo...

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Detalles Bibliográficos
Autores principales: Momeni, Mohsen, Mashayekhi, Kazem, Navashenaq, Jamshid Gholizadeh, Sankian, Mojtaba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9218155/
https://www.ncbi.nlm.nih.gov/pubmed/35756119
http://dx.doi.org/10.1016/j.heliyon.2022.e09721

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9218155/
https://www.ncbi.nlm.nih.gov/pubmed/35756119
http://dx.doi.org/10.1016/j.heliyon.2022.e09721

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