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Identification of G-quadruplex anti-Interleukin-2 aptamer with high specificity through SELEX stringency
Aptamers are short single-stranded oligonucleotides capable of binding to various targets with high specificity and affinity. This study aimed to identify an aptamer against mouse interleukin-2 (mIL-2) as one of the most important cytokines in autoimmune diseases for diagnostic and therapeutic purpo...
Autores principales: | Momeni, Mohsen, Mashayekhi, Kazem, Navashenaq, Jamshid Gholizadeh, Sankian, Mojtaba |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9218155/ https://www.ncbi.nlm.nih.gov/pubmed/35756119 http://dx.doi.org/10.1016/j.heliyon.2022.e09721 |
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