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STING signaling sensing of DRP1-dependent mtDNA release in kupffer cells contributes to lipopolysaccharide-induced liver injury in mice

Aberrant pro-inflammatory activation of Kupffer cells (KCs) is strongly involved in the pathogenesis of septic liver injury. Recent evidence indicates the crucial roles of excessive stimulator of interferon genes (STING) signaling activation during sepsis. However, the role of STING signaling in sep...

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Detalles Bibliográficos
Autores principales: Zhang, Qin, Wei, Jiayi, Liu, Zhuanhua, Huang, Xiaoxia, Sun, Maomao, Lai, Wujiang, Chen, Zhenfeng, Wu, Jie, Chen, Yanjia, Guo, Xiaohua, Huang, Qiaobing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9218162/
https://www.ncbi.nlm.nih.gov/pubmed/35724543
http://dx.doi.org/10.1016/j.redox.2022.102367