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Machine learning-guided evaluation of extraction and simulation methods for cancer patient-specific metabolic models

Genome-scale metabolic model (GEM) has been established as an important tool to study cellular metabolism at a systems level by predicting intracellular fluxes. With the advent of generic human GEMs, they have been increasingly applied to a range of diseases, often for the objective of predicting ef...

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Detalles Bibliográficos
Autores principales: Lee, Sang Mi, Lee, GaRyoung, Kim, Hyun Uk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9218235/
https://www.ncbi.nlm.nih.gov/pubmed/35782748
http://dx.doi.org/10.1016/j.csbj.2022.06.027