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Coxiella burnetii Affects HIF1α Accumulation and HIF1α Target Gene Expression

HIF1α is an important transcription factor regulating not only cellular responses to hypoxia, but also anti-infective defense responses. We recently showed that HIF1α hampers replication of the obligate intracellular pathogen Coxiella burnetii which causes the zoonotic disease Q fever. Prior to deve...

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Detalles Bibliográficos
Autores principales: Hayek, Inaya, Szperlinski, Manuela, Lührmann, Anja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9218251/
https://www.ncbi.nlm.nih.gov/pubmed/35755850
http://dx.doi.org/10.3389/fcimb.2022.867689