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Organoid-derived intestinal epithelial cells are a suitable model for preclinical toxicology and pharmacokinetic studies

Intestinal organoids are physiologically relevant tools used for cellular models. However, the suitability of organoids to examine biological functions over existing established cell lines lacks sufficient evidence. Cytochrome P450 3A4 (CYP3A4) induction by pregnane X receptor ligands, glucose uptak...

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Detalles Bibliográficos
Autores principales:	Takahashi, Yu, Noguchi, Makoto, Inoue, Yu, Sato, Shintaro, Shimizu, Makoto, Kojima, Hirotatsu, Okabe, Takayoshi, Kiyono, Hiroshi, Yamauchi, Yoshio, Sato, Ryuichiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9218437/ https://www.ncbi.nlm.nih.gov/pubmed/35754737 http://dx.doi.org/10.1016/j.isci.2022.104542

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