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Inhibitory and stimulatory micropeptides preferentially bind to different conformations of the cardiac calcium pump
The ATP-dependent ion pump sarco/endoplasmic reticulum Ca(2+)-ATPase (SERCA) sequesters Ca(2+) in the endoplasmic reticulum to establish a reservoir for cell signaling. Because of its central importance in physiology, the activity of this transporter is tightly controlled via direct interactions wit...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9218510/ https://www.ncbi.nlm.nih.gov/pubmed/35605666 http://dx.doi.org/10.1016/j.jbc.2022.102060 |