Inhibitory and stimulatory micropeptides preferentially bind to different conformations of the cardiac calcium pump

The ATP-dependent ion pump sarco/endoplasmic reticulum Ca(2+)-ATPase (SERCA) sequesters Ca(2+) in the endoplasmic reticulum to establish a reservoir for cell signaling. Because of its central importance in physiology, the activity of this transporter is tightly controlled via direct interactions wit...

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Detalles Bibliográficos
Autores principales: Cleary, Sean R., Fang, Xuan, Cho, Ellen E., Pribadi, Marsha P., Seflova, Jaroslava, Beach, Jordan R., Kekenes-Huskey, Peter M., Robia, Seth L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9218510/
https://www.ncbi.nlm.nih.gov/pubmed/35605666
http://dx.doi.org/10.1016/j.jbc.2022.102060

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