Cargando…

StemPanTox: A fast and wide-target drug assessment system for tailor-made safety evaluations using personalized iPS cells

An alternative model that reliably predicts human-specific toxicity is necessary because the translatability of effects on animal models for human disease is limited to context. Previously, we developed a method that accurately predicts developmental toxicity based on the gene networks of undifferen...

Descripción completa

Detalles Bibliográficos
Autores principales: Yamane, Junko, Wada, Takumi, Otsuki, Hironori, Inomata, Koji, Suzuki, Mutsumi, Hisaki, Tomoka, Sekine, Shuichi, Kouzuki, Hirokazu, Kobayashi, Kenta, Sone, Hideko, Yamashita, Jun K., Osawa, Mitsujiro, Saito, Megumu K., Fujibuchi, Wataru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9218511/
https://www.ncbi.nlm.nih.gov/pubmed/35754715
http://dx.doi.org/10.1016/j.isci.2022.104538