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PACT establishes a posttranscriptional brake on mitochondrial biogenesis by promoting the maturation of miR-181c
The double-stranded RNA-dependent protein kinase activating protein (PACT), an RNA-binding protein that is part of the RNA-induced silencing complex, plays a key role in miR-mediated translational repression. Previous studies showed that PACT regulates the expression of various miRs, selects the miR...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9218515/ https://www.ncbi.nlm.nih.gov/pubmed/35598827 http://dx.doi.org/10.1016/j.jbc.2022.102050 |