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PACT establishes a posttranscriptional brake on mitochondrial biogenesis by promoting the maturation of miR-181c

The double-stranded RNA-dependent protein kinase activating protein (PACT), an RNA-binding protein that is part of the RNA-induced silencing complex, plays a key role in miR-mediated translational repression. Previous studies showed that PACT regulates the expression of various miRs, selects the miR...

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Detalles Bibliográficos
Autores principales: Dogan, Asli E., Hamid, Syed M., Yildirim, Asli D., Yildirim, Zehra, Sen, Ganes, Riera, Celine E., Gottlieb, Roberta A., Erbay, Ebru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9218515/
https://www.ncbi.nlm.nih.gov/pubmed/35598827
http://dx.doi.org/10.1016/j.jbc.2022.102050