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A novel tubulin inhibitor, 6h, suppresses tumor-associated angiogenesis and shows potent antitumor activity against non–small cell lung cancers

Tumor angiogenesis is closely associated with the metastasis and progression of non–small cell lung cancer (NSCLC), a highly vascularized solid tumor. However, novel therapeutics are lacking for the treatment of this cancer. Here, we developed a series of 2-aryl-4-(3,4,5-trimethoxy-benzoyl)-5-substi...

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Detalles Bibliográficos
Autores principales: Liu, Zi, Huang, Liancheng, Zhou, Tianhao, Chang, Xing, Yang, Yuying, Shi, Yani, Hao, Mingjing, Li, Zengqiang, Wu, Yingliang, Guan, Qi, Zhang, Weige, Zuo, Daiying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9218517/
https://www.ncbi.nlm.nih.gov/pubmed/35618020
http://dx.doi.org/10.1016/j.jbc.2022.102063