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Adenosine-A(2A) Receptor Signaling Plays a Crucial Role in Sudden Unexpected Death in Epilepsy

Adenosinergic activities are suggested to participate in SUDEP pathophysiology; this study aimed to evaluate the adenosine hypothesis of SUDEP and specifically the role of adenosine A(2A) receptor (A(2A)R) in the development of a SUDEP mouse model with relevant clinical features. Using a combined pa...

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Detalles Bibliográficos
Autores principales: Shen, Hai-Ying, Baer, Sadie B., Gesese, Raey, Cook, John M., Weltha, Landen, Coffman, Shayla Q., Wu, Jie, Chen, Jiang-Fan, Gao, Ming, Ji, Teng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9218562/
https://www.ncbi.nlm.nih.gov/pubmed/35754505
http://dx.doi.org/10.3389/fphar.2022.910535