Cargando…

Renoprotection of Microcystin-RR in Unilateral Ureteral Obstruction-Induced Renal Fibrosis: Targeting the PKM2-HIF-1α Pathway

Renal fibrosis is a pathological characteristic of the endpoint of chronic kidney disease (CKD), which remains a major public health problem. None of the current therapies is effective in stopping kidney fibrosis progression. In light of our novel detection of a potential antifibrosis of microcystin...

Descripción completa

Detalles Bibliográficos
Autores principales: Ren, Yan, Wang, Jie, Guo, Wenwen, Chen, Jingwen, Wu, Xin, Gu, Shubo, Xu, Lizhi, Wu, Zhiwei, Wang, Yaping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9218570/
https://www.ncbi.nlm.nih.gov/pubmed/35754468
http://dx.doi.org/10.3389/fphar.2022.830312