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Efficient embryoid-based method to improve generation of optic vesicles from human induced pluripotent stem cells

Animal models have provided many insights into ocular development and disease, but they remain suboptimal for understanding human oculogenesis. Eye development requires spatiotemporal gene expression patterns and disease phenotypes can differ significantly between humans and animal models, with pati...

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Detalles Bibliográficos
Autores principales: Eintracht, Jonathan, Harding, Philippa, Lima Cunha, Dulce, Moosajee, Mariya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9218590/
https://www.ncbi.nlm.nih.gov/pubmed/35811797
http://dx.doi.org/10.12688/f1000research.108829.1