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Epigenetic Therapeutics Targeting NRF2/KEAP1 Signaling in Cancer Oxidative Stress

The transcription factor nuclear factor erythroid 2-related factor 2 (NRF2) and its negative regulator kelch-like ECH-associated protein 1 (KEAP1) regulate various genes involved in redox homeostasis, which protects cells from stress conditions such as reactive oxygen species and therefore exerts be...

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Detalles Bibliográficos
Autores principales: Zhang, Shunhao, Duan, Sining, Xie, Zhuojun, Bao, Wanlin, Xu, Bo, Yang, Wenbin, Zhou, Lingyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9218606/
https://www.ncbi.nlm.nih.gov/pubmed/35754474
http://dx.doi.org/10.3389/fphar.2022.924817