CREB Ameliorates Osteoarthritis Progression Through Regulating Chondrocytes Autophagy via the miR-373/METTL3/TFEB Axis

Osteoarthritis (OA) is a degenerative joint disease characterized by articular cartilage degradation. Dysregulated autophagy is a major cause of OA. However, the underlying mechanism is unclear. Here, we found that the expression of element-binding protein (CREB) was downregulated in both cartilage...

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Detalles Bibliográficos
Autores principales: Zhang, Haibin, Li, Xilei, Li, Yusheng, Yang, Xucheng, Liao, Runzhi, Wang, Haoyi, Yang, Junxiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9218638/
https://www.ncbi.nlm.nih.gov/pubmed/35756079
http://dx.doi.org/10.3389/fcell.2021.778941

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9218638/
https://www.ncbi.nlm.nih.gov/pubmed/35756079
http://dx.doi.org/10.3389/fcell.2021.778941

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