Single‐Cell RNA Sequencing Reveals Heterogeneity of Myf5‐Derived Cells and Altered Myogenic Fate in the Absence of SRSF2

Splicing factor SRSF2 acts as a critical regulator for cell survival, however, it remains unknown whether SRSF2 is involved in myoblast proliferation and myogenesis. Here, knockdown of SRSF2 in myoblasts causes high rates of apoptosis and defective differentiation. Combined conditional knockout and...

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Detalles Bibliográficos
Autores principales: Guo, Ruochen, You, Xue, Meng, Kai, Sha, Rula, Wang, Zhenzhen, Yuan, Ningyang, Peng, Qian, Li, Zhigang, Xie, Zhiqin, Chen, Ruijiao, Feng, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9218650/
https://www.ncbi.nlm.nih.gov/pubmed/35460187
http://dx.doi.org/10.1002/advs.202105775

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9218650/
https://www.ncbi.nlm.nih.gov/pubmed/35460187
http://dx.doi.org/10.1002/advs.202105775

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