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Single‐Cell RNA Sequencing Reveals Heterogeneity of Myf5‐Derived Cells and Altered Myogenic Fate in the Absence of SRSF2
Splicing factor SRSF2 acts as a critical regulator for cell survival, however, it remains unknown whether SRSF2 is involved in myoblast proliferation and myogenesis. Here, knockdown of SRSF2 in myoblasts causes high rates of apoptosis and defective differentiation. Combined conditional knockout and...
Autores principales: | Guo, Ruochen, You, Xue, Meng, Kai, Sha, Rula, Wang, Zhenzhen, Yuan, Ningyang, Peng, Qian, Li, Zhigang, Xie, Zhiqin, Chen, Ruijiao, Feng, Ying |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9218650/ https://www.ncbi.nlm.nih.gov/pubmed/35460187 http://dx.doi.org/10.1002/advs.202105775 |
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