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Optimal combination of cationic lipid and phospholipid in cationic liposomes for gene knockdown in breast cancer cells and mouse lung using siRNA lipoplexes

Formulation of cationic liposomes is a key factor that determine the gene knockdown efficiency by cationic liposomes/siRNA complexes (siRNA lipoplexes). Here, to determine the optimal combination of cationic lipid and phospholipid in cationic liposomes for in vitro and in vivo gene knockdown using s...

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Detalles Bibliográficos
Autores principales: Hattori, Yoshiyuki, Tang, Min, Torii, Satomi, Tomita, Kana, Sagawa, Ayane, Inoue, Nodoka, Yamagishi, Reo, Ozaki, Kei-Ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9218728/
https://www.ncbi.nlm.nih.gov/pubmed/35686555
http://dx.doi.org/10.3892/mmr.2022.12769