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Single‐cell RNA Sequencing Identified Novel Nr4a1(+) Ear2(+) Anti‐Inflammatory Macrophage Phenotype under Myeloid‐TLR4 Dependent Regulation in Anti‐Glomerular Basement Membrane (GBM) Crescentic Glomerulonephritis (cGN)

Previously, this study demonstrates the critical role of myeloid specific TLR4 in macrophage‐mediated progressive renal injury in anti‐glomerular basement membrane (anti‐GBM) crescentic glomerulonephritis (cGN); however, the underlying mechanism remains largely unknown. In this study, single‐cell RN...

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Detalles Bibliográficos
Autores principales: Chen, Jiaoyi, Huang, Xiao Ru, Yang, Fuye, Yiu, Wai Han, Yu, Xueqing, Tang, Sydney C. W., Lan, Hui Yao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9218767/
https://www.ncbi.nlm.nih.gov/pubmed/35484716
http://dx.doi.org/10.1002/advs.202200668