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Nurr1 Modulation Mediates Neuroprotective Effects of Statins

The ligand‐sensing transcription factor Nurr1 emerges as a promising therapeutic target for neurodegenerative pathologies but Nurr1 ligands for functional studies and therapeutic validation are lacking. Here pronounced Nurr1 modulation by statins for which clinically relevant neuroprotective effects...

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Detalles Bibliográficos
Autores principales: Willems, Sabine, Marschner, Julian A., Kilu, Whitney, Faudone, Giuseppe, Busch, Romy, Duensing‐Kropp, Silke, Heering, Jan, Merk, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9218776/
https://www.ncbi.nlm.nih.gov/pubmed/35488520
http://dx.doi.org/10.1002/advs.202104640