Identification of a Subtype-Selective Allosteric Inhibitor of GluN1/GluN3 NMDA Receptors

N-methyl-D-aspartate receptors (NMDARs) are Ca(2+)-permeable ionotropic glutamate receptors (iGluRs) in the central nervous system and play important roles in neuronal development and synaptic plasticity. Conventional NMDARs, which typically comprise GluN1 and GluN2 subunits, have different biophysi...

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Detalles Bibliográficos
Autores principales: Zeng, Yue, Zheng, Yueming, Zhang, Tongtong, Ye, Fei, Zhan, Li, Kou, Zengwei, Zhu, Shujia, Gao, Zhaobing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9218946/
https://www.ncbi.nlm.nih.gov/pubmed/35754487
http://dx.doi.org/10.3389/fphar.2022.888308

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9218946/
https://www.ncbi.nlm.nih.gov/pubmed/35754487
http://dx.doi.org/10.3389/fphar.2022.888308

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