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Identification of a Subtype-Selective Allosteric Inhibitor of GluN1/GluN3 NMDA Receptors
N-methyl-D-aspartate receptors (NMDARs) are Ca(2+)-permeable ionotropic glutamate receptors (iGluRs) in the central nervous system and play important roles in neuronal development and synaptic plasticity. Conventional NMDARs, which typically comprise GluN1 and GluN2 subunits, have different biophysi...
Autores principales: | Zeng, Yue, Zheng, Yueming, Zhang, Tongtong, Ye, Fei, Zhan, Li, Kou, Zengwei, Zhu, Shujia, Gao, Zhaobing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9218946/ https://www.ncbi.nlm.nih.gov/pubmed/35754487 http://dx.doi.org/10.3389/fphar.2022.888308 |
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