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CXCL10(+) peripheral activation niches couple preferred sites of Th1 entry with optimal APC encounter

Correct positioning of T cells within infected tissues is critical for T cell activation and pathogen control. Upon tissue entry, effector T cells must efficiently locate antigen-presenting cells (APC) for peripheral activation. We reveal that tissue entry and initial peripheral activation of Th1 ef...

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Detalles Bibliográficos
Autores principales: Prizant, Hen, Patil, Nilesh, Negatu, Seble, Bala, Noor, McGurk, Alexander, Leddon, Scott A., Hughson, Angela, McRae, Tristan D., Gao, Yu-Rong, Livingstone, Alexandra M., Groom, Joanna R., Luster, Andrew D., Fowell, Deborah J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9218982/
https://www.ncbi.nlm.nih.gov/pubmed/34380032
http://dx.doi.org/10.1016/j.celrep.2021.109523