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CXCL10(+) peripheral activation niches couple preferred sites of Th1 entry with optimal APC encounter
Correct positioning of T cells within infected tissues is critical for T cell activation and pathogen control. Upon tissue entry, effector T cells must efficiently locate antigen-presenting cells (APC) for peripheral activation. We reveal that tissue entry and initial peripheral activation of Th1 ef...
Autores principales: | Prizant, Hen, Patil, Nilesh, Negatu, Seble, Bala, Noor, McGurk, Alexander, Leddon, Scott A., Hughson, Angela, McRae, Tristan D., Gao, Yu-Rong, Livingstone, Alexandra M., Groom, Joanna R., Luster, Andrew D., Fowell, Deborah J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9218982/ https://www.ncbi.nlm.nih.gov/pubmed/34380032 http://dx.doi.org/10.1016/j.celrep.2021.109523 |
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